D e p a r t m e n t   o f

Molecular Biology & Biotechnology

  • Molecular Biology Research
  • Molecular Biology Research
  • Molecular Biology Research
  • Molecular Biology Research
  • Molecular Biology Research

The areas of research pursued are:

  • Studies on hydrolytic enzymes from carnivorous plants.
  • Genetic diversity of Rhizobia
  • Evaluating the species limits of endemic plant Genera by DNA barcoding
  • Genetic diversity of plants
  • Biodegrading microbes and enzymes.
  • Development and characterization of functional textile materials with antimicrobial activities

PhD Research

Diversity of Cycad species in Sri Lanka and their morphological and biochemical characterization

Supervisors: Prof. GAD Perera, Prof. S.D.S.S. Sooriyapathirana, Dr. P Samaraweera
Student: Mudannayake MMAWP

Human gene expression analysis as a molecular marker to determine the causative agent in patients with chronic kidney disease of unknown etiology (CKDu) in Sri Lanka

Supervisors: Dr. Magana-Arachchi DN, Prof. S.D.S.S. Sooriyapathirana
Student: Sayanthooran S

Regulation of auxin signaling in plants during stress response; A molecular genetics study on Aux/IAA transcription repressor gene family.

Supervisors: Dr. P. Sapathanthri, Dr. N. Dharmasiri, Prof. S. Rajapakse, Prof. S.D.S.S. Sooriyapathirana
Student: Dhanapala MPCS

MPhil Research

Molecular identification and drug susceptibility of Non-tuberculous Mycobacteria (NTM)

Supervisors: Dr. Magana-Arachchi DN, Prof. Sooriyapathirana SDSS
Student: Keerthiratne TP

MSc

DNA based detection of meat adulterations in mutton, Sri Lanka

Supervisors: Prof. Sooriyapathirana SDSS
Student: Mahipalan A

Molecular phylogenetic analysis of Artocarpus species in Sri Lanka.

Supervisors: Prof. Sooriyapathirana SDSS
Student: Ratanasuriya A

Morphological and genetic diversity of Luffa aegyptiaca (sponge gourd) germplasm in Sri Lanka

Supervisors: Prof. Sooriyapathirana SDSS
Student: Kumari SASM

Morphological and genetic diversity of Solanum germplasm in Sri Lanka

Supervisors: Prof. Sooriyapathirana SDSS
Student: Dissanayake RMN

Morphlogical and genetic diversity of Manihot esculenta germplasm in Sri Lanka

Supervisors: Prof. Sooriyapathirana SDSS
Student: Dissanayake UHK

Morphological and phylogenetic analysis of Artocarpus heterophyllus in Sri Lanka

Supervisors: Prof. Sooriyapathirana SDSS
Student: Senanayake RB

Optimization of PCR conditions for DNA barcoding markers in genus Artocarpus

Supervisors: Prof. Sooriyapathirana SDSS
Student: Hariharan G

Each final year honors degree student has to complete a research project, which is supervised by the academic staff members. There are several research projects related to Molecular Life sciences every year. The projects are evaluated in a seminar and a report. This project provides opportunity for students to conduct scientific research independently and to improve the skills in Molecular Biological techniques and ethics.

2016/2017 Academic Year

Assessment of the marker trait association between yield parameters and polymorphism of the GHD7 locus in a core set of rice genotypes grown in Sri Lanka

Supervisors: Prof. S. D. S. S. Sooriyapathirana
Student: N. D. U.S. Nakandala (S/12/174)

Assessment of the Phosphorus deficiency tolerance in a selected set of rice varieties and their DNA marker haplotypes of the Pup1 locus

Supervisors: Prof. S. D. S. S. Sooriyapathirana, Dr. U. A. K. S. Udawela
Student: H. S. M. Jayarathne (S/12/216)

Backcross breeding of rice with foreground and background genomic selection for Brown Planthopper resistance

Supervisors: Prof. S. D. S. S. Sooriyapathirana, Dr. U. A. K. S. Udawela
Student: R. M. S. K. Rathnayake (S/12/105)

Detection of mecA gene and Methicillin resistance in Staphylococci isolated from the human oral cavity

Supervisors: Prof. R. G. S. C. Rajapakse, Prof. Sumedha Jayathilleke
Student: W. M. D. A. Wijesundara (S/12/196)

Establishment of varietal identity of selected exportable and mega production rice genotypes in Sri Lanka using DNA fingerprinting and sequencing

Supervisors: Prof. S. D. S. S. Sooriyapathirana
Student: W. W. M. U. K. Wijesundara (S/12/177)

Expression of a few Aux/IAA genes in some selected rice varieties under the stress induced by Mannitol and Polyethylene Glycol

Supervisors: Mrs. M. P. C. S. Dhanapala
Student: H. M. Y. Y. Bandara (S/12/229)

Expression of a some Aux/IAA genes in rice during Salicylic Acid treatment and Rice Blast Infection

Supervisors: Mrs. M. P. C. S. Dhanapala
Student: R. R. M. D. S. Rathnayake (S/12/179)

Identification of the species limits and assessment of the phytochemical diversity and consumer preference of the widely grown accessions of four leafy vegetables in Sri Lanka

Supervisors: Prof. S. D. S. S. Sooriyapathirana
Student: T. H. I. Gayathree (S/12/222)

Phylogenetic relationships and population genetic structure of Stone Sucker, Garra ceylonensis (Cyprinidae, Labeonini) in the Mahaweli Ichthyological Province, Sri Lanka

Supervisors: Prof. M. P. B. Meegaskumbura
Student: H. M. T. N. Senavirathna (S/12/149)

Physiological characterization and genetic diversity assessment of the Rhizobial populations inhabiting Gliricidia sepium in Ampara District, Sri Lanka

Supervisors: Prof. R. G. S. C. Rajapakse
Student: P. W. I. Nawanjana (S/12/193)

Purification and characterization of Chitinase(s) from Pitcher fluid of Nepenthes distillatoria

Supervisors: Prof. R. G. S. C. Rajapakse
Student: R. W. K. M. Senevirathna (S/12/191)

Species identification and habitat associations of larval fresh water fish through DNA barcoding in the Central Hills of Sri Lanka

Supervisors: Prof. M. P. B. Meegaskumbura
Student: A. P. Amarasinghe (S/12/158)

The effect of salt stress on expression of some Aux/IAA genes in different rice varieties in Sri Lanka

Supervisors: Mrs. M. P. C. S. Dhanapala
Student: U. G. S. Janesha (S/12/210)

2017/2018 Academic Year

Analysis of genetic diversity and population structure of Colletotricum sp. on different fruit and vegetables in Sri Lankan market

Supervisors: Mrs. M. P. C. S. Dhanapala
Student: M. B. Shaima (S/13/202)

Biotic and Abiotic Stresses on Rice

Supervisors: Prof. S. D. S. S. Sooriyapathirana
Student: M. N. R Rizna (S/13/213)

Cellulytic fungi

Supervisors: Prof. P. Samaraweera
Student: A. K .A. U Jayathissa (S/13/201)

Characterization of fatty acid profile of Madhuca longifolia (Mee)

Supervisors: Mrs. M. P. C. S. Dhanapala
Student: B. A. K. T Premachandra (S/13/247)

Climatic effects and genetic diversity on fruit quality of Syzugium sp. (Roseapple)

Supervisors: Prof. S. D. S. S. Sooriyapathirana
Student: D. G. P.K. Senevirathne (S/13/246)

Cross inoculation studies of selected Rhizobial strains on crop legumes

Supervisors: Prof. R. G. S. C. Rajapakse
Student: S. M. N. S. Samarakoon (S/13/172)

Genetic diversity of potential strains of Trichoderma isolates for biological control

Supervisors: Mrs. M. P. C. S. Dhanapala
Student: D. W. G. A. S Alukumbura (S/13/241)

Genetic diversity of a tree species in Sri Lanka

Supervisors: Prof. S. D. S. S. Sooriyapathirana
Student: W. G. A. S. Sumanarathne (S/13/226)

Investigation on oral microflora

Supervisors: Prof. R. G. S. C. Rajapakse, Prof. Sumedha Jayathilleke
Student: M. A. D. K. S. Mallikarachchi (S/13/085)

Microbial lipases

Supervisors: Prof. P. Samaraweera
Student: G. D. Kariyawasam (S/13/210)

Petroleum degrading bacteria isolation and characterization

Supervisors: Prof. P. Samaraweera
Student: K. M. A. Karunathilaka (S/13/071)

Preliminary study on identification of urinary mRNA biomarkers for CKDu

Supervisors: Dr. Saumya Wickramasinghe
Student: S.M. Sahibdeen (S/13/116)


Past Undergraduates Research Projects